Para Protein Gap
Paraproteins are monoclonal immunoglobulins or immunoglobulin fractions that are produced by a clonal population of B-cell lineage cells. The level of globulin in the serum is derived by subtracting the albumin concentration from the total protein. Pdf The Gamma Gap And All Cause Mortality 04052012 Raised serum globulin or total protein or both is often the first indication of the presence of a paraprotein. Para protein gap . Paraproteins are monoclonal immune globulin fragments or intact immune globulins produced by usually a malignant cone of plasma cells or B cells. PARAPROTEINS GP REFERRAL GUIDELINES Introduction Disorders characterised by the production of a paraprotein include monoclonal gammopathy of undetermined significance MGUS multiple myeloma and Waldenstrms macroglobulinaemia. Paraprotein gap is sometimes used as a screening tool in some autoimmune diseases cancers and screening for latent infections. When a raised globulin level is found it is important to de